Guide to Electrophysiological Recording • 31
Chapter 4
Chapter 4
A Practical Guide to Electrophysiological
Recording Using the MultiClamp 700A
The purpose of this chapter is to provide practical advice on patch clamping and sharp
microelectrode recording, both of which are possible using the MultiClamp 700A. It
includes both tutorial-style guidance and technical details for reference. This
information has been distilled from textbooks on the subject (see References at the end
of this manual) and from experienced researchers working in laboratories around the
world. However, as is the case for all advice (and particularly that pertaining to
research), the suggestions given here should be taken as provisional until they have
been tested in your own circumstances.
This chapter has been divided into three parts: (1) general advice for in vitro
electrophysiology, (2) patch clamping, and (3) sharp microelectrode recording.
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