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7.3 HFM insertion
Prior to use, HFM may require wetting with water or buffer. In general, prior to use, please read
the separate Hollow Fiber Module Preparation Instructions that are included with every hollow
fiber. There are different preparation methods depending on the module type purchased.
Two types of HFMs are available for the XCell™ ATF System; accordingly, two types of Filter
Housings are available:
• S-line Housing for use with HFM with “O” rings on the HFM ends for sealing against
the housing inner diameter.
• I-line Housing for use with HFM with no attached “O” rings. The “O” ring is placed
in a recess at the housing ends, between HFM and Reducer (or Diaphragm Pump).
Clamping the connection between Reducer (or Diaphragm Pump) and the Filter
Housing squeezes the “O” ring effectively forcing the “O” ring against the filter
wall, effectively sealing the three parts.
Figure 8. Types of Filter Housings
1.3.1 S-Line HFM insertion:
b1. Lay the Filter Housing horizontally and insert HFM (without “O” rings) into the
Filter Housing.
Step b2 is to avoid damage to the “O” ring during its insertion and sliding into the housing,
to avoid crossing the Harvest port opening during insertion, as the Drain port is close to the
housing end.
b2. Expose HFM at the Filter Housing end distant to drain port, in proximity to the
Filtrate / Harvest port.
b3. Place an “O” ring in the exposed HFM “O” ring groove.
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