6.2.1 Important considerations for cleaning
Cleaning frequency
A suitable frequency of routine cleaning is determined by the nature of the starting
material and the type of process. However, routine cleaning shall be performed at
intervals aimed at prevention rather than cleaning the system from growth or contami-
nation.
Cleaning before
maintenance/service
The system must be thoroughly cleaned to remove any infectious or aggressive fluids
before maintenance or service.
Recommended cleaning agents
All components can be cleaned with the most commonly used agents, such as detergents,
ethanol, weak acids, sodium hydroxide and salt solutions.
Refer to Section 8.2 Chemical resistance, on page 167.
NOTICE
Avoid sodium chloride solutions below pH 4.0. Rinse the system
thoroughly with water immediately after it has been in contact
with salt solutions.
Clean the UV and conductivity
cell
The UV cell and conductivity cells are cleaned by flushing the cells with 1 M sodium hy-
droxide or 20% ethanol.
136 ÄKTAprocess Operating Instructions 29-0252-49 AA
6 Maintenance
6.2 Cleaning
6.2.1 Important considerations for cleaning
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