REPLIGEN KrosFlo SYITF-2000 User Manual

KrosFlo® Systems
User Guide
23
IF.UG.IM_R1
9.2 Cassette Holder Assembly (optional)
9.2.1 Cassettes Installation
Figure 7. Cassette Installation
To install cassettes into the holder:
1. Place the single-use Center Manifold into the holder first. (Blue Arrow)
Note:
• The feed and retentate ports need to face the System’s main recirculation pump.
• The ports are clearly labeled.
2. Properly and evenly extend out the 2 end nuts (Green Arrow) by loosening them to the
proper length, a length that can accommodate all required cassettes on each side.
Note:
• If only one cassette is used, then it should be placed up on the fixed side or piston-
end (left side), followed by the Center Manifold.
3. Add cassettes from the fixed end plate (Gray Arrow) towards the Center Manifold.
a. Start with Solid Plastic End Plate (Orange Arrow) against metal facing side.
b. Then add a cassette block.
c. Wet the gasket, then install it right next to the cassette block.
d. Repeat steps b) and c) above until the required number of cassettes is installed.
Note:
• A gasket must be wetted and installed between a cassette and the Center Manifold.
• Gaskets need to be aligned carefully and should not block channels on the cassettes.
4. Repeat everything in step 3) on the movable end plate (Red Arrow), to get an equal
number of membrane “blocks” on each side of the Center Manifold.
Note:
• Another Solid Plastic end plate should be installed between the movable end plate
and a cassette block.
5. Slide movable end plate (Red Arrow) up against the cassettes, as close as possible.
6. Tighten two end nuts (Green Arrow), leaving an approximate ¼” gap to the endplate.
End nuts (x2)
Movable end plate
Solid Plastic
End Plate
Center Manifold
Solid Plastic End Plate
Fixed End Plate

REPLIGEN KrosFlo SYITF-2000 Specifications

General

Brand	REPLIGEN
Model	KrosFlo SYITF-2000
Category	Laboratory Equipment
Language	English