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13. Performing System Maintenance
The KrosFlo® System is of robust design and intended for use with process equipment. As such, lab
or plant cleanliness and care are all that is needed to ensure quality operation when used in the
System’s intended manner.
Refer to section 3 for detailed Safety Guidelines. An Electrical Schematic and a list of all major
components (Process and Control Panel items) is also provided with the System should any service
be required.
13.1 Making the System Safe for Maintenance
Before performing adjustments and maintenance on the System, you must make the System safe by
following these steps:
1. If possible, flush the System.
2. Shut down the System properly (see Appendix section).
3. Lockout the System in accordance with the System owner’s lockout/tagout procedures.
4. Wear the PPE required by the System owner’s safety program.
5. Verify again that all power sources, utilities, and chemicals have been removed from the
System.
13.2 Cleaning the System
The frame, cabinet, and pumps can be cleaned by manual wipe-down using mild cleaning agents
and/or warm water and a damp cloth or lab wipes. The HMI/Touchscreen should be cleaned with
computer screen cleaner and computer screen wipes.
Cleaning products are readily available from supply houses and the user must make sure the
selected agent(s) are acceptable with their facility and compliant with System materials of
construction.
13.3 Cleaning the Flow-path
Thoroughly clean and flush the flow-path with purified water and allow it to drain and dry – if
possible.
Alternately, the flow-path may be stored full of a suitable storage buffer if it is to remain in place
until the next use. Ensure that thermal expansion is thoroughly considered and calculated, or
environmental temperature must be maintained at an appropriate temperature.
Repligen does not recommend use of Vaporized Hydrogen Peroxide (VHP) to
clean the KrosFlo system.
WARNING – Refer to section 3 for Safety Precautions
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