USP Operation
MXD70 Conductivity Setup and
Operating Guide
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USP Operation
Conductivity USP Operation
US Pharmacopoeia is used by all pharmaceutical companies as a standard set of procedures to ensure
that they will comply with FDA requirements. This is applied to conductivity measurements (Section
645), which are used to determine if the water used as either a washing solution or as part of the
product being manufactured meets strict quality standards.
The Directive
Conductivity is used as the first (Stage 1) test and can be an on-line measurement. The measurement is
used to determine the maximum level of dissolved minerals that are in the solution, which it is ideally
suited to do. However the conductivity of a solution varies with temperature as well as the
contaminants in it, and this temperature dependence varies with the type of contaminant. In order to
compensate for this most conductivity instrument s apply a temperature compensation factor, usually
2%/°C, but due to the wide variation in the quality of different manufacturers temperature
compensation systems USP has specified that all measurements must be made uncompensated. The
table below lists the maximum allowed conductivity values at a series of different temperatures.
μS/cm °C μS/cm °C μS/cm °C
0.6 0 1.4 30 2.2 60
0.8 5 1.5 35 2.4 65
0.9 10 1.7 40 2.5 70
1.0 15 1.8 45 2.7 75-90
1.1 20 1.9 50 2.9 95
1.3 25 2.1 55 3.1 100
USP Operation
Any setpoint which is assigned to a conductivity input channel can be set to activate in accordance
with the limits specified in the USP standard.
Main Menu
From the front screen press the menu button to
show the main menu options and select Setpoint /
Relays.
/ – Select Option
EXIT
– Return to Front Screen
– Enter Option
Select Setpoint
Select the Setpoint you wish to edit.
/ – Select Option
EXIT
– Return to Main Menu
– Enter Option
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