Chapter 7: Functional description
7-16 Fresenius Medical Care multiFiltrate IFU-EN-UK 15A-2015
7.3 Anticoagulation
Requirement for
anticoagulation
When performing extracorporeal blood treatments, anticoagulation of
the blood is generally required. It prevents coagulation in the
extracorporeal blood circuit and ensures an adequate operating life of
the filters used.
7.3.1 Systemic anticoagulation
Systemic anticoagulants Different substances, such as unfractionated or fractionated heparin,
Danaparoid, Argatroban, can be used for anticoagulation.
The selection and dosage of the suitable substance are determined by
the physician. Depending on the substance, different laboratory
parameters are used to control the dosage. The aPTT (activated partial
thromboplastin time), for example, is a suitable parameter to assess the
effect of unfractionated heparin in principle.
Integrated heparin pump
for anticoagulation
A heparin pump for the continuous infusion of diluted heparin is
integrated in the device. This pump can also be used to administer a
bolus when required. An infusion line for anticoagulants is included in
the tubing system.
Fig.: Schematic of systemic anticoagulation
Legend 1 Blood pump
2 Haemofilter
3 Air detector
4 Venous clamp
5 Heparin pump
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