Art: 714376-00M Rev. Date: 31-Jan-12 14-5
Target Values
Target values (determined by testing multiple ampules of each level using
multiplelotsofcartridgesandi-STATanalyzersthathavepassedtheElectronic
Simulatortest)areprintedonavalueassignmentsheetpostedontheAPOC
websiteatwww.abbottpointofcare.com.
Alwaysbesurethatthelotnumberprintedontheinsertmatchesthelotnumber
onthelabeloftheampuleinuse,andthatthesoftwarerevisionabovethe
targetvaluetablematchesthesoftwarerevisionintheanalyzer.
Therangesdisplayedrepresentthemaximumdeviationexpectedwhencontrols
and cartridges are performing properly.
Shouldresults outside the ranges be obtained, refertothe Troubleshooting
sectionthatfollowstheProcedureforTestingControls.
Target Values are specific to the i-STAT System. Results obtained from these
aqueouscontrolswithothermethodsmaydifferduetosamplematrixeffects.
Correction of PO
2
at
Extreme Altitude
Thepartialpressureofoxygeninasolutionwillchangeasitequilibratesto
the surrounding ambient pressure. The rate of change is faster in aqueous
solutionsthaninwholebloodduetotheabsenceofredbloodcellscontaining
hemoglobinwhichbindsoxygenmolecules.Thisisofpracticalsignicance
when testing aqueous solutions on blood gas analyzers as there will be a
detectableshiftinthepartialpressureofoxygeninthesampleasitequilibrates
tothepressureintheowpathoftheanalyzer.
The ranges for i-STAT aqueous control solutions are established for the degree
of oxygen equilibration whichoccurs in the cartridges at or near sea level.
PO
2
resultsforaqueoussolutions,includingi-STATcontrolsandCalibration
Verication Set and prociency (external quality control) samples, can be
corrected for higher altitude environments using the following equations.
Observed PO
2
values should be corrected before comparing them to the values
inthevalueassignmentsheetincludedwitheachboxofi-STATcontrols.
Equations:
For PO
2
valuesbelow150mmHg:
PO
2
corrected = PO
2
observed+(0.067x(760–BP))
WhereBPisthebarometricpressurereadingfromtheAnalyzer
Status screen.
(Approximatechange:Foreverydecreaseof15mmHginpressurefrom
760mmHg,add1mmHgtoobservedvalue.)
For PO
2
valueabove150mmHg:
PO
2
corrected = PO
2
observed+(0.029x(760–BP))
WhereBPisthebarometricpressurereadingfromtheAnalyzer
Status screen.
(Approximatechange:Foreverydecreaseof35mmHginpressurefrom
760mmHg,add1mmHgtoobservedvalue.)
Ranges
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