Roche Diagnostics
B-22 Operator’s Manual · Version 3.1
5 Daily operation Cedex Bio System
Preparing the system
Preparing the reagents
Reagents are handled in sets. A set consists of up to three reagents. If for example one
reagent bottle of a set is empty, all reagents of the set need to be replaced. The system
only uses reagents of complete sets.
On the screen, each set is represented by a separate button.
Use reagents of the same lot, if possible
When replacing a new reagent set, try to use one of the same lot as the old one. This way
you avoid having to perform a calibration.
Diluent and cleaner bottles
An extra diluent or cleaner bottle is considered one set. Extra cleaners and diluents are
handled in the same type of bottles that are used for reagents. Their handling works the
same way. In the following, the process is described for reagents.
Make sure that you have read and understood section Safety information on page B-5. The
following warning messages in particular are relevant:
o Injury through reagents and other working solutions on page B-5.
o Infection by biohazardous materials on page B-5.
o Loss of sight on page B-6.
o Personal injury or damage to the analyzer due to contact with instrument mechanism on
page B-5.
Incorrect results due to declining reagent quality
Due to the declining quality of reagents, the quality of measurement may decline. This may
cause incorrect results.
Make sure to use reagents whose expiration date has not passed yet.
Incorrect results due to reagent dilution through condensation
In conditions of high temperature and humidity, condensation can build up inside the
reagent bottles. This leads to dilution of the reagent.
In such conditions and when not performing tests, especially if you observe condensation
on the reagent disk or in the reagent cooler, be sure to remove the reagent disk from the
instrument and place it in the reagent disk container. Close the container with its lid and
place it in a refrigerator.
Incorrect results due to condensation in the reagent cooler
In conditions of high temperature and humidity, condensation can build up in the reagent
cooler. Water can spill on the analyzer unit and get into the cuvettes when removing the
reagent disk.
In conditions of high temperature and humidity, be sure to periodically wipe up the con-
densation water in the reagent cooler.
Incorrect results due to inappropriate reagent handling
Removing and loading reagents while the reagent disk is outside the instrument may lead
to inconsistencies between the recorded and the physically loaded reagents and conse-
quently to incorrect results.
Always remove and load reagents while the reagent disk is on the instrument and by using
the software supported procedures.
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